Polynucleotide vs Fillers
Three differences between polynucleotides and fillers.
1. Polynucleotides are DNA fragments extracted from salmon, whereas fillers are either cross-linked hyaluronic acid or other synthetic polymers.
2. Safety Synthetic polymers or cross-linked hyaluronic acid fillers can block the blood vessels, which can cause a severe complication such as necrosis or dying of the tissue and/or blindness.
Whereas, polynucleotides are very safe, in the 10 years that it's been out in the market, there has still been zero cases of vascular compromise or blockage of the blood vessel.
3. As we age, we do lose volume, and a lot of this volume loss is due to depletion of the bone or bone reabsorption. So areas where that happens, you're gonna lose volume. So fillers can help to replace that volume in those areas immediately. On the other hand, polynucleotides can help to improve your skin quality. It stimulates collagen and can also hydrate the skin. So whereas it is less effective in creating volume, it can still help you naturally improve your skin and other tissue quality inside your face for more natural results.
5 Reasons Why PN Treatments Can Help You Age Gracefully
Here are five reasons why polynucleotide treatments can help you age gracefully.
1. They are anti-inflammatory, which helps to reduce redness and swelling after aesthetic procedures or skin damage.
2. It increases circulation as ageing reduces our blood circulation.
3. It stimulates growth factors, which stimulate cells to make more collagen in the tissue.
4. PN treatments help repair damaged DNA. This reduces the number of DNA damaged fragments that is caused from either intrinsic or extrinsic factors.
5. Mitochondria. What's that you may ask? There are actually energy factories inside our body. Polynucleotide treatments such as Rejuran can increase the number of mitochondria, therefore improving the functionality of mitochondria.
Insight into Polynucleotide Scaffold
Just last month, my article was published in a SCI journal and it described the scaffolding structure of DOT Polynucleotide. This is the first time that we know of that the structure of Polynucleotides that we use in aesthetic medicine, has been published in our journal. One of the most important points is that there was a difference between the structure of PDRN and PN because PDRN actually has no structure, there is no scaffolding inside PDRN, whereas DOT Polynucleotide actually does have a scaffold structure. So moving forward, this helps us to understand how DOT Polynucleotides can help patients in their aesthetic journey.
If you're also interested in doing some aesthetic treatments, improving your skin quality, elasticity of your tissue, then DOT Polynucleotide can be an option.
Boosting Treatment Efficacy: Polynucleotide Scaffold
Here's a little sneak peek into the future. Moving forward with the scaffold structure of DOT PN, there are a few possible implications and applications that we can consider.
Number one: Due to the scaffold structure, we can have stem cell differentiations. So certain stem cells can develop into different types of cells that we need in our body.
Number two: We can also combine this scaffold with other products to have a longer lasting effect. If you look at the structure of the scaffold, you can see there are empty spaces inside the scaffold. When you combine them with different proteins of cells and deliver that to a certain area, it can increase the efficacy of that treatment.
Number three: The scaffold can also help to improve the environment that surrounds cells, and this is important in aging because what we have found is that it's not always the cells that are to blame for aging but the area and the environment that are surrounding the cells that cause the cells to age.
So by injecting this type of DOT PN scaffold, we can improve the matrix around the cells and hopefully slow down the process of aging or maybe even reverse it.
Polynucleotides in Action: Fat Atrophy Edition
I recently published a letter in a SCI journal about 2 cases that I treated here in Singapore. The first case is a female who had sunkenness on one temple after she had some injections done in Korea to dissolve the fat, but it was too much, and so she had a crater like sunkenness in one of her temples. So after treatment with polynucleotide over multiple sessions, we were able to see improvement in that area and that improvement was very safe. There was no inflammation and it was long lasting over a year. So these are pieces of information that will help you to make a more informative decision if you have fat atrophy.
Of course not all fillers have these side effects. They can be quite rare, but it's important that you do know that they are possible. And when it comes to polynucleotides and replacing volume in fat atrophy, it's still very early stage and there's still much research that we have to do to find out the effectiveness and safety moving forward.
Polynucleotides: Aiding Sensitive Skin
Another regenerative effect is that polynucleotides can help to repair the damaged DNA from UV radiation and inflammation that is happening inside the skin. So as of now, there is no definitive cure for sensitive skin, unfortunately. However, over time with more research, polynucleotides do have the potential to help to improve and maybe even cure some sensitive skin conditions. But remember to always consult with your medical professional for more medical advice.
Unlock Skin Elasticity with Polynucleotides
DOT Polynucleotides or DOTPN is another name for what you commonly know as Rejuran. DOT stands for DNA Optimizing Technology, and it is proprietary to the company that creates Rejuran. The structure of Rejuran looks sort of like a honeycomb, and we call this a scaffold. So as we grow older, our skin loses its elasticity. And how do we restore that elasticity?
Scaffolding of the DOT PN when it's injected into the skin can help to restore the elasticity of the skin, specifically in the dermis and the collagen fibers in the fat layer. So you can think of the scaffold sort of like a sponge. The sponge is very elastic, even though we compress it, if we let go it will also regain its shape. So the scaffolding has this elasticity to it, which is also something that could happen inside the skin.
Top 5 Benefits of Increased Mitochondria
Benefits of increased mitochondria.
1. Enhanced energy: Feel more energized throughout the day, whether you're working, exercising, or just simply enjoying life.
2. Improve cellular health: Mitochondria support better cellular function, which can benefit your organs, skin, and overall vitality.
3. Anti aging benefits: Mitochondrial health is linked to the ageing process. More mitochondria can mean slower ageing and a youthful feel.
4. Better skin: Healthy mitochondria contribute to glowing, radiant skin, reinforcing Rejuran's aesthetic benefits.
5. Boosted immunity: A thriving cellular powerhouse helps fortify your immune system for a healthier you. So embrace the science of beauty and vitality with Rejuran and experience the difference it can make inside and out.
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