Rejuran (POLYNUCLEOTIDE-PN)

Polynucleotide (PN) used in Rejuran is a type of biological molecule similar to DNA in cells and is extracted from salmon. The main reason salmon was used is because salmon DNA was found to have beneficial effects on human skin and the DNA is very similar to human DNA. Researchers found that salmon DNA is safe and it is purified to prevent side effects such as allergic reactions. PN can help the skin by providing anti-inflammatory and wound healing mechanisms which in turn can help to stimulate collagen and improve hydration and elasticity of the skin.

Rejuran is a good skin dehydration treatment option, that helps in minimising enlarged pores. Here are its other benefits:

• Improved skin texture and reduced pores
• Improvement in skin laxity and fine wrinkles
• Reduces skin dehydration
• Improvement of skin barrier function and facilitation of the healing processes in the skin (de novo pathway)
• Recovery of skin balance – of sebum and moisture in the skin.
• Safety: Highly bio-compatible DNA fragments with no serious adverse reactions
• Natural results: This does not alter the features of your face (like most fillers) but addresses the fundamental problem of skin damage and skin quality.
• Accurate Placement: Each site is injected manually by Dr Kim directly into the proper layer of skin to achieve the desired results.

Rejuran is most effective when injected into the superficial level of the skin where pain can be more intense. Therefore, a numbing cream will be applied prior to the treatment to reduce the pain, but mild-moderate pain is felt during the injections. The needle is very small to minimise the pain – even smaller than those used for “botox”. Once the procedure is finished there will usually be no more pain.

After cleansing by our therapist, numbing cream will be applied to the areas to be treated for about 45 minutes. After the numbing cream is removed, the procedure itself will take about 20-40 min depending on the size of the areas to be treated. After the injection treatment, you will be brought back to your private room where a Rejuran PDRN mask will be applied with simultaneous LED treatment for 15 minutes to enhance the recovery process. Therefore the total time needed may reach 2 -2.5 hours in the clinic.

You will have redness and swelling (“bumps” which look like small mosquito bites) on the injection sites for 1-2 days after the day of the treatment. You are advised to stay indoors for 24-48 hours after the treatment to avoid external damage from the sun, pollutants, or cosmetics. The visible “bumps” will usually subside within 24 hours.

You should not apply make-up for 24-48 hours to avoid unnecessary clogging of the injection sites which may lead to acne or infection. You should also avoid prolonged exposure to sunlight, and extreme temperatures, using saunas or Turkish baths, massages, and strenuous exercise for two weeks after the injection.

For optimal results, it is advised to do 3-4 sessions at 3-4 week intervals. Results may take more than 3-4 weeks after the 3rd or 4th session and results may vary according to the individual due to genetic and environmental factors. You are reminded that this is NOT a “filler” injection for augmentation of the face, so obvious visible changes in facial features will not be seen.

REJURAN is composed of biocompatible DNA fragments very similar to our body; studies have shown no severe side effects such as tolerance or immunological /allergic responses after the administration of the product. Common side effects would be redness, swelling and pain which will resolve in 24-28 hours. Bruising is rare, but if it occurs, it can last 1-2 weeks but will resolve.

Rejuran-i is the same as Rejuran Healer but in a thinner form allowing easier injection into the areas around the eyes which are more sensitive and have thinner skin. This also allows faster recovery after injection. This product can help with the fine wrinkles around the eyes and in some cases (results vary) help improve the appearance of dark eye circles after 3-4 sessions at 1-month intervals. Compared to Rejuran Healer which has 2 ml per syringe, each syringe of Rejuran-i has 1 ml. To treat areas around the eye, 1 syringe is usually recommended. This can be done in combination on the same day with treatments like lasers and other injections like Rejuran Healer.

Rejuran–s is the same as Rejuran Healer but in a thicker form allowing injection into scarred areas which usually have more dense tissue and skin. This also allows the product to remain longer in the area for longer results after injection. This product can help with some types of scars (results vary) after 3-4 sessions at 1-month intervals. Compared to Rejuran Healer which has 2 ml per syringe, each syringe of Rejuran-s has 1 ml. Depending on the area of scars to be treated, the amount needed will be determined. In the case of acne scars, this can be done in combination on the same day with Rejuran Healer for other parts of the face/neck and/or other acne scar treatments such as Venus Viva. For more information on multiple treatment options, call our aesthetic clinic in Singapore today!